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CHEE 450: Engineering Biology


Teaching Assistants:

Phil Fernandes

Eric Peterson

Course Instructor:

Dr. R. J. Neufeld (neufeld@queensu.ca)
Biosciences 1443 (near Tim Horton's!!!)

neufeld

 

NOTE FOR JANUARY 2011, THIS COURSE WILL SURFACE ON A MOODLE SITE. THIS WEBSITE THEN HAS BECOME OBSOLETE..... STAY iTUNED.

 


Check this out: 2010

Latest on Canadian HIV-vaccination facility

Update on the HIV vaccine manufacturing facility: Canadian HIV Vaccine Initiative (Feb. 19)

Canada, Gates Foundation scrap HIV vaccine plant (Jan. 28)

Research group perspective (Feb.24)

MP grills officials over cancellation (Apr. 13)

Flaws in report to shelve HIV-vaccine facility (Mar. 18)

Great information source - Corning (Apr. 1)

Good job search advice from graduate (Apr. 1)

Colbert's blood cells are out there... somewhere (Mar. 31, thanks to J.L.)

Good news for some alcohol drinkers.... thanks to enzyme engineering (Mar. 30)

The Immortal Life of Henrietta Lacks (Mar. 29 - thanks to J.L.)

Pfizer and GSK deal, brokered by GAVI Alliance to supply low cost pneumonia vaccines to poorest countries (Mar. 25)

FDA biopharmaceutical product approvals for 2009 (Mar. 24)

Cost data for process equipment (Mar. 23 - thanks to A.K.)

Stem cells derived from umbilical cords (Mar. 23)

Automated cell counting technology (Mar. 22)

China's growing strength in stem cell research (Mar. 18)

Live and work in Ireland? then you need to know about Hurling (Mar. 17)

Spend St. Patrick's Day checking out biotech/biomed jobs in Ireland (Mar. 17)

For a good time... (Mar. 16)

Bioreactor based production of morphine/codeine developed at Univ. Calgary (Mar. 15)

Canadian breakthrough in Hodgkin's lymphoma treatment (Mar. 11)

Kingston's Millenium Biologix reinvents itself as Octane Medical Group (Mar. 10) - thanks to L.V.

Explanation of "The Inner Life of the Cell (Mar. 9)

The Inner Life of the Cell (Mar. 9)

Information on Engineering approaches to a pandemic (Mar. 8)

PCR explained (Mar.4)

Question is, are you worth the big bucks? (Mar. 3)

Enviropig??? (Thanks to D.C.) (Mar. 2)

Technical report writing suggestions (Mar. 1)

Simple method to stabilize vaccines (Feb. 18)

Interesting case study with lack of H1N1 response in Poland (Feb. 17)

Schwarzenegger endorsed home ethanol system - E-fuel MicroFueler (imagine the possibilities!) (Feb. 11)

Canadian Farmaceutical stories (Feb. 4)

Insulin from safflower - Sembiosys

BioSteel from goat milk - Nexia

Verging on the AIDs vaccine? (Feb. 3)

Harper's Illustrated Biochemistry, 26th Ed., by Robert K. Murray et al. (Knovel e-books) (Feb. 3)

Review the following chapters

3. Amino acids and peptides

4. Proteins - primary structure

5. Proteins - higher orders of structure

13. Carbohydrates of physiologic significance

14. Lipids of physiologic significance

What would you do with $10,000,000,000? (Feb. 2)

Bio Numbers (Feb. 1)

It pays to be a chemical engineering chemist (Feb. 1)

Can you imagine the body as a bioreactor? (Jan. 28): contributed by Sarah Haw

Few interesting links related to Jana Dengler's talk yesterday (Jan. 27)

Pick a heart, any heart

Proof that it beats (check out suppmentary movie 1 - gruesome... and movie 4 - ok)

How about a heart muscle robot?

Questioning the future of biofuels in Canada (Jan. 25)

Advice from Sci'08 toward admissions to medicine (Jan. 21)

Home cell culture assignment (Jan. 21)

How to save your ass as an engineer (Jan. 20)

Biograd study locations in Canada (Jan. 19)

H1N1 tracker (Jan. 18)

High pay equal high expectations for chee/ench grads (Jan. 13)

Investment in Bioplastics (Jan. 12)

Pick a protein, any protein (Jan. 11)

 

 

This and that: 2009

Check out supplementary movies 1 through 4 for images of decellularized and reseeded hearts (Apr. 15)

Unconventional approach to treating antibiotic-resistant infection (Mar. 31 with thanks to Joe S.)

Musicians for better PCR (Mar. 30)

Course evaluation (Mar. 25)

10 things chemists should know about chemical engineers (Mar. 25)

10 things chemical engineers should know about chemists (Mar. 25)

Case for Serum-Free Media (Mar. 20)

Response to question on glycerol production (Mar. 20)

Who can you trust? (Mar. 20)

Looking into the cell (Mar. 18)

Synthetic Genome first (Mar. 16)

Synthetic Genomics Inc. (Mar. 16)

Media reporting on Canadian development around induced pluripotent stem cells (iPS cells) (Mar. 13)

Report 1 (Canadian media)

Report 2 (UK media)

Kaji's paper published in Nature (Mar. 16)

Advice for getting into meds (Mar. 11)

Immortality? Invasion of the jellyfish!! (Mar. 9)

I saw a student wearing a T-shirt today that said "Size Matters". I wondered about that until I saw this... (Mar. 9)

Producing recombinant proteins without needing a cell line? Is this artificial life? (Mar. 9)

Interesting Canadian company: Biophage Pharma: (Mar. 9)

Principle of cell sorting (Mar. 5)

Original piggyBac paper in Nature (Mar. 3)

Canadian stem cell breakthrough (Mar. 2)

First tissue-engineered whole organ transplant, formed with patient's own stem cells (Feb. 23)

Good resource on bioprocess information: chech out article on insulin purification (Feb. 13)

Pause to remember Louis Pasteur (Feb. 11)

Can the world eradicate polio? (thanks Richard) (Jan. 30)

International Aids Vaccine Initiative - iavi (Jan. 28)

Ontario immunization schedule (Jan. 26)

Life on Mars? (Jan. 23)

They keep us in the dark and feed us sh&* (Jan. 21)

Presentation on iGEM competition with thanks to Harry Z. (Jan. 19)

$1,000,000 (US) prize (Jan. 19)

Reversal expected on stem cell research in USA (Jan. 15)

Biograduate study locations in Canada (Jan. 14)

Microbially produced superoxide radicals damage DNA in gut cells, potentially leading to cancer (Jan. 14)

McDonald's "healthy" food choices include bioprocess based ingredients (Jan. 12)

Bioreactor capability in Canada (Jan. 8)

Bioengineering research in Canada (Jan. 8) (from Biotechnology Progress, for personal use only)

Good advice for future graduate students (Jan. 7)

Career guide for Biomedical Engineering (Jan. 7)

Items in the news: 2008

Novel hand held blood immunoassay kit (Mar. 31)

Proof positive that Prof. N. takes a camera into men's washrooms. "No flush" means "hands free" for photography in the interests of bioscience (Mar. 31)

Microencapsulated Islet implantation (Mar. 24)

Development around Parkinson's (Mar. 24)

Preprint of article on Bioengineering in Canada from Biotechnology Progress (for personal use only): (Mar. 24)

Contaminant found in heparin imports (Mar. 24)

Spectactular bio-images (Mar. 20)

Synchrotron imaging of Norwalk RNA polymerase enables design of inhibitor (Mar. 19)

Enzymes designed in silico to react with substrates not found in nature - thanks Elliott (Mar. 19)

Creating synthetic life - talk by Craig Venter (Mar. 18): contributed by Mike Hull (graduate of chee 450)

World-wide biomanufacturing capability (Mar. 19)

Mitochondrial on/off switch (Mar.17)

Excellent education videos supplied by Daniel on microbiology and on water (Mar. 12)

Heart muscle robot (Mar. 14)

Breathalyzer test for cancer (Mar. 13)

Dummy Guide to cloning "muffin" (Mar. 12)

Cloning of "muffin" (Mar. 10)

Antibiotic pipline drying up? (Mar. 10)

Visit from Cangene on Wednesday, Mar. 5

Flow cytometry (Mar. 3) and micro cell sorting based on dielectrophoresis (thanks Elliott)

HIV blocking gene - Canadian discovery (thanks Dan) (Mar. 3)

Take a culture, any culture... (Feb. 28)

Resurgence of TB in North America (Feb. 28)

Possible grad study locations in Canada in Biochemical/Biomedical Engineering (Feb. 27)

Transformation of human skin cells into stem cells (Feb. 25)

Plant derived "oral" insulin- SemBioSys (Feb. 25)

Dr. J. Craig Venter lecture (A DNA driven World - thanks Elliott) (Feb. 25)

International AIDS Vaccine Initiative (IAVI) (Feb. 14)

Bacterial cell scaffolding (Feb. 14)

Canadian protocol on islet transplants exported to the UK (Feb. 11)

New approach toward targeting cancer cells (Feb. 11)

Spectacular 3D animation of the inner life or the cell (Feb. 4)

C. difficile (Feb. 4)

Attacking the superbug (Feb. 4)

Botoxicology (Jan. 31)

WHO tracking of H5N1 (Jan. 30)

Open wide and say ahhh - Thanks M.E. (Jan. 29)

Tracking bird flu (Jan. 28)

Rabies scare in Ontario (Jan. 28)

Bioreactors? of the future - Thanks Jonas (Jan. 24)

Recipe for great bread (Jan. 21)

Human-animal embryo research approved (Jan. 21)

Care to clone yourself? (Jan. 21)

Nature Medicine article - engineering a new heart (Jan. 17)

I have a heart for you (Jan. 14)

Bioreactor capability in Canada (Jan. 14)

McDonald's Ingredients (Jan. 14)

Musicians for better PCR (Jan. 14)

Universal flu vaccine? (Jan. 10)

Bug r' us detection system (Jan. 9)

Treatment of diabetes using implanted beta cells (Jan. 7, 2008)

You call that news? (left over from 2007)

New source of stem cells (Jan. 8, 2007)

Injectable vaccine for cervical cancer? (Jan. 9, 2007)

Upper Canada Ethanol (Jan. 9, 2007)

Blood, Sweat & Tears: David Clayton-Thomas (Canadian)

More on Blood, Sweat & Tears: Genencor (Jan. 15)

Engineering Approaches to a Pandemic: note presentation by David Estell, VP Technology at Genencor (Jan. 16)

Living Fed-Batch bioreactor? (Jan. 17)

Goat'a be kid'n (Jan. 17)

First recombinant protein from animal: Nature Biotechnology (Jan. 18)

GTC Biotherapeutics (Jan. 23)

Crunch time for AIDS vaccine: contributed by Aaron McGregor (Jan. 24)

Inactivated versus attenuated oral polio vaccine use in Canada (Jan. 25)

Transmission of polio (Jan. 25)

Outbreak of bird flu in Japan (Jan. 29)

Spread of bird flu/H5N1 (Jan. 29)

Canadian Immunization guide (Jan. 30)

Ontario Immunization guide (Jan. 30)

Nature Genetics: Tyrosine phosphatase deficiency or inhibition delays breast cancer in mice (Jan. 31)

Super yeast as ethanol producers (Feb. 1)

But look what does to the price of corn! (Feb. 1)

US House or Representatives passes embryonic stem cell bill (Feb. 5)

Check out baculovirus protein expression system (BEVS) at Protein Sciences Corp. (Feb. 8)

Gene for type 2 diabetes discovered (Feb. 14)

Link to Nature article dealing with diabetes gene - thanks Kristen (Feb. 15)

Check out article 15 in Jan 07 issue of Discover

New alternatives to embryonic stem cells (Feb. 26)

New bladder anyone? (Feb. 27)

New approaches to fighting HIV (Feb. 28)

Wonder what it will do for exam performance? - the saga of Lance Armstrong (Mar. 1)

The smell of cancer (Mar 5)

Human metabolism reduced to a computer model (Mar. 6)

HIV has a chink in its armour (Mar. 7)

New affinity resin removes prions from blood plasma (Mar. 12)

Aerobic/anaerobic on/off switch (Mar. 13)

TB vaccine is no longer effective? unbelievable! (Mar. 14)

Good article on insulin purification (Mar. 15)

Biotech jobs south of border (Mar. 15)

Disclaimer: Prof. N. does not regularly visit male contraceptive websites!! (Mar. 19)

Gene therapy - OK, but in utero? (Mar. 20)

First islet transplantation - Toronto (Mar. 21)

Jobs, jobs, jobs (Mar. 21)

More recent info around jobs (Mar. 26)

Spectacular SEM photomicrographs - check out the image(s) on islets and microencapsulated islets (Mar. 26)

The following news items are left over from 2006

Stem cell fraud published in Science

Stem cell paper 1 published in Science

Stem cell paper 2 published in Science

Snuppy cloned! published in Nature: note the article immediately following by Queen's Chemistry profs on Green Chemistry

Green pigs and ham: http://news.bbc.co.uk/1/hi/world/asia-pacific/4605202.stm

Toronto blood stem cell initiative published in Experimental Hematology

Controversy around Taxol: http://www.sptimes.com/2005/12/25/State/Keep_your_millions__F.shtml

Mice can regrow hearts?: http://www.worldhealth.net/p/its-a-miracle---mice-regrow-hearts-2005-09-16.html

IOGEN representatives speaking in ChemEng/EngChem department tonight: Jan. 23, 2006

Does E.coli age?: check out p. 0185

Production of human pancreatic stem cells capable of producing islet cells in culture for transplantation

Manufacture of flu vaccine: Microbix

Baculovirus expression system

Which came first, the sperm or the egg?

Virgin birth?

Yeast promotes nasal delivery of insulin (yeast as delivery vehicle for protein drugs?)

Improved insulin now available in Canada

Olympic dopers - what were they taking?

Nanosurgery under confocal microscope

Canadian islet transplant pioneers honored: Edmonton protocol

Good slides around carbohydrate chemistry

Genetic control of aerobic/anaerobic metabolism

GlycoFi announce production of human glycosylated antibodies using yeast

Canadian biotech

Engineering approaches to vaccine production

Topoisomerases help cell untangle 3 m of DNA

Aspirin prevents platelets from sticking together and so prevents clotting

Final word on Dr. Hwang? (contributed by W.M.)

Molecular knitting of DNA? (contributed by W.M.)

TB antibiotics based on knowledge of metabolic pathway

Stem cell treatment anyone?

SouthWest Research Institute: Microencapsulation and Controlled Release specialists

Ink Jet printer spits out cells

Cloned pigs produce omega-3 fatty acids, but will the consumer bring home the bacon?

Relenza joins Tamiflu as second FDA approved antiviral

Integrated Grain Processors Co-operative building $90 million ethanol plant in Aylmer

Lab-produced bladder transplant using patients own cells (contributed by B.T.)

Looks like link between alcohol and tumor angiogenesis linked through expression of vascular endothelial growth factor (contributed by ultrafiltration design team)

 


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