Strategies for Process Investigations
The statistical design of experiments and the analysis of data in process investigations are considered. Empirical modelling of process behaviour is studied. Applications of factorial and fractional factorial experimental designs in screening studies and methods of response surface exploration are examined. Traditional North American approaches to quality and productivity improvement are compared with those practiced in Japan.
Model Based Control
The course focuses on the use of explicit process models for multi-variable controller design. Linear and nonlinear control approaches are discussed in both discrete and continuous time formulations. Stability, performance and robustness issues are addressed. The role of observers for state estimation is considered.
A survey of optimization problems is made and mathematical procedures for their solutions are discussed. Comparisons of optimization techniques for various classes of problems are made using industrial examples and computer studies. Both linear and nonlinear programming methods are studied. Topics include the role of optimization, definitions of objective functions and constraints, conditions for existence of an optimum; one-dimensional strategies; analytical procedures for unconstrained and constrained multi-dimensional problems, numerical procedures for unconstrained and constrained multidimensional problems, and introduction to multistage optimization.
Polymer Reaction Engineering
The fundamentals of polymerization kinetics are reviewed. The equations for batch and continuous flow reactors are developed and used in the calculation of polymerization rate and polymer quality measures. Process parameters which affect reaction rate, chain composition and molecular weight distribution are examined, and the design of polymer reactor systems is discussed. Consideration is also given to the problems of reactor design in heterophase polymerization.
This course is designed as a graduate level introductory course in tissue engineering: the interdisciplinary field that encompasses biology, chemistry, medical sciences and engineering to design and fabricate living systems to replace damaged or diseased tissues and organs. Topics to be discussed include: tissue anatomy, basic cell biology, cell scaffolds, cell sources and differentiation, design considerations, diffusion and mass transfer limitations, effects of external stimuli, bioreactors, methods used to evaluate the engineered product(s), and implantation. Case studies of specific tissue engineering applications will also be discussed. Students will be required to participate in, as well as lead, discussions on the course material and relevant journal articles.
Structure-Property Relationships of Polymeric Materials
This six-week graduate module provides students with background in physical polymer science as it relates to the formulation of materials to satisfy engineering applications. Starting from the characterization of molecular weight and composition distributions, the fundamentals of phase transitions, solubility, adhesion and thermo-oxidative stabilization are discussed.