Journal Publications

R. Chapanian, M.Y. Tse, S.C. Pang, and B.G. Amsden, "Long term in vivo degradation and tissue response to photo-cross-linked elastomers prepared from star-shaped prepolymers of poly(ε-caprolactone-co-D,L-lactide)," J Biomed Mater Res A 92A, 830-842, 2010.

B. Ilagan and B.G. Amsden, "Macroporous photocrosslinked elastomer scaffolds containing microporosity: preparation and in vitro degradation properties," J. Biomed. Mater. Res. A 93A, 211-218, 2010.

J. Hayami, D. Surrao, S.D. Waldman, and B.G. Amsden, "Composite scaffold for ligament tissue engineering," J. Biomed. Mater. Res. A 92A, 1407-1420, 2010.

R. Chapanian and B.G. Amsden, "Osmotically driven protein release from photo-cross-linked elastomers of poly(trimethylene carbonate) and poly(trimethylene carbonate-co-D,L-lactide)," Eur. J. Pharm. Biopharm. 74, 172-183, 2010.

R. Chapanian and B.G. Amsden, "Combined and sequential delivery of bioactive VEGF165 and HGF from poly(trimethylene carbonate) based photo-cross-linked elastomers," J. Controlled Release 143, 53-63, 2010.

B. Amsden and B. Qi, "Anti-atherosclerotic peptide delivery from a photocrosslinkable biodegradable network," Int. J. Pharmaceutics 388, 32-39, 2010.

L. Timbart, MY Tse, SC Pang, and BG Amsden, "Tissue response to, and degradation rate of, photocrosslinked trimethylene carbonate-based elastomers following intramuscular implantation," Materials: Special Issue Advances in Biomaterials 3, 2, 1156-1171, 2010.

B. Amsden, "Liquid, injectable, hydrophobic and biodegradable polymers as drug delivery vehicles," Macromolecular Bioscience 10, 8, 825-835, 2010.

A.Hsieh, T Zahir, Y Lapitsky, B. Amsden, W. Wan, MS Shoichet, "Hydrogel/Electrospun Fiber Composites Influence Neural Stem/Progenitor Cell Fate," Soft Matter 6, 10, 2227-2237, 2010.

BG Amsden, L. Timbart, D. Marecak, M.Y. Tse, SC Pang, "VEGF –induced angiogenesis following localized delivery from injectable low viscosity poly(trimethylene carbonate)," J Controlled Release 145, 109-115, 2010.

DC Surrao, JWS Hayami, SD Waldman, BG Amsden, "Self Crimping Electrospun Polymer Fibres," Biomacromolecules 11, 3624-3629, 2010.

L. Timbart, M.Y. Tse, S.C. Pang, O. Babasola, B.G. Amsden, "Low viscosity poly(trimethylene carbonate) for localized drug delivery: rheological properties and in vivo degradation," Macromolecular Bioscience 9, 786-794, 2009.

B. Ilagan and B.G. Amsden, "Surface modifications of photocrosslinked biodegradable elastomers and their influence on smooth muscle cell adhesion and proliferation," Acta Biomaterialia 5, 7, 2429-2440, 2009.

R. Chapanian, M.Y. Tse, S.C. Pang, and B. Amsden, "Role of oxidation and enzymatic action in the in vivo degradation of trimethylene carbonate based photocrosslinkable elastomers," Biomaterials 30, 3, 295-306, 2009 [More information].

L. Timbart and B.G. Amsden, "Functionalizable biodegradable photocrosslinkable elastomers based on 2-oxepane-1,5-dione," J Polym Sci A Polym Chem 46, 24, 8191-8199, 2008 [More information].

B.G. Amsden and A. Lau, "Siloxane based copolymers for use in two-phase partitioning bioreactors," Can J Chem Eng 86, 1-5, 2008 [More information].

B. Amsden, G.P. Misra, M. Marshall, ND Turner, "Synthesis and characterization of biodegradable networks providing saturated-solution prolonged delivery," J Pharm Sci 97, 849-862, 2008 [More information].

B. Amsden, "Drug delivery from biodegradable elastomers," Expert Opinion on Drug Delivery 5, 175-187, 2008 [More information].

V. Wang, G Misra, and B. Amsden, "Immobilization of a bone and cartilage stimulating peptide to a synthetic bone graft," J Mater Sci Mater Med 19, 2145-2155, 2008 [More information].

D.K. Knight, S. Shapka, and B. Amsden, "Structure, depolymerization, and cytocompatibility evaluation of glycol chitosan," J Biomed Mater Res A 83A, 787-798, 2007 [More information].

B. Amsden, A. Sukarto, D.K. Knight, and S.N. Shapka, "Methacrylated glycol chitosan as a photopolymerizable biomaterial," Biomacromolecules 8, 12, 3758-3766, 2007 [More information].

F. Gu, R. Neufeld, and B. Amsden, "Stabilization of bioactive VEGF and potentially other therapeutic proteins during a photo-initiated free radical cross-linking reaction forming biodegradable elastomers," Eur J Pharm Biopharm 66, 21-27, 2007 [More information].

S. Sharifpoor and B. Amsden, "In vitro release of a water-soluble agent from low viscosity biodegradable, injectable oligomers," Eur J Pharm Biopharm 65, 336-345, 2007 [More information].

F. Gu, RJ Neufeld, B. Amsden, "Sustained release of bioactive therapeutic proteins from a cylindrical biodegradable elastomeric device," J Control Release 117, 80-89, 2007 [More information].

B. Amsden, "Review of osmotic pressure driven release of proteins from monolithic devices," J Pharm Pharmaceut Sci 10, 2, 100-114, 2007 [More information].

B. Amsden, "Curable elastomers: Emerging biomaterialsfor drug delivery and tissue engineering ," Soft Matter 3, 11, 1335-1348, 2007 [More information].

A. Mikhail, S. Sharifpoor, and B. Amsden, "Initiator structure influence on thermal and rheological properties of oligo(e-caprolactone)," J. Biomater. Sci. Polym Edn 17, 291-301, 2006 [More information].

F. Gu, RJ Neufeld, and BG Amsden, "Osmotic driven release kinetics of bioactive therapeutic proteins from a biodegradable elastomer are linear, constant, similar and adjustable," Pharm Res 23, 4, 782-789, 2006 [More information].

Y. Zhang and B. Amsden, "Diffusion of vitamin B12 and proteins in semidilute alginate solutions under physiological conditions," Macromolecules 39, 1073-1078, 2006 [More information].

B. Amsden, M. Y. Tse, N.D. Turner, D.K. Knight, and S.C. Pang, "In vivo degradation behavior of photo-cross-linked star-poly(e-caprolactone-co-D,L-lactide) elastomers," Biomacromolecules 7, 365-372, 2006 [More information].

A. Tomkins, M. Kontopoulou, and B. Amsden, "Preparation and characterization of blends of star-poly(e-caprolactone-co-D,L-lactide) and oligo(e-caprolactone)," J. Biomater. Sci. Polym. Edn. 16, 1009-1021, 2005 [More information].

F. Gu, H.M. Younes, A.O.S. El-Kadi, R. Neufeld, B. Amsden, "Sustained interferon-y delivery from a photocrosslinked biodegradable elastomer," J. Control. Release 102, 607-617, 2005 [More information].

B.G. Amsden, G. Misra and F. Gu, "Synthesis and characterization of a photo-crosslinked biodegradable elastomer," Biomacromolecules 5, 6, 2479-2486, 2004 [More information].

B.G. Amsden, B.G. Stubbe, F. Horkay, S.C. De Smedt, and J. Demeester, "Modeling the swelling pressure of degrading DEX-HEMA hydrogels," J. Polym. Sci. B. Polym. Phys. 42, 3397-3404, 2004 [More information].

B. Amsden, S. Wang, and U. Wyss, "Synthesis and characterization of thermoset biodegradable elastomers based on star-poly(e-caprolactone-co-D,L-lactide)," Biomacromolecules 5, 4, 1399-1404, 2004 [More information].

F. Gu, B. Amsden, R.J. Neufeld, "Sustained delivery of vascular endothelial growth factor using alginate beads," J. Control. Release 96, 463-472, 2004 [More information].

A. Hatefi, D. Knight, and B. Amsden, "A biodegradable injectable thermoplastic for localized camptothecin delivery," J. Pharm. Sci. 93, 1195-1204, 2004 [More information].

H.M. Younes, E. Bravo-Grimaldo, and B. Amsden, "Synthesis, characterization and in vitro degradation of a biodegradable elastomer," Biomaterials 25, 5261-5269, 2004 [More information].

B. Amsden, A. Hatefi, D. Knight, E. Bravo-Grimaldo, "Development of injectable biodegradable thermoplastic oligomers," Biomacromolecules 5, 637-642, 2004 [More information].

B. Amsden, "A model for osmotic pressure driven release from cylindrical rubbery polymer matrices," J. Control. Release 93, 249-258, 2003 [More information].

B.G. Amsden, J. Bochanysz, and A.J. Daugulis, "Degradation of xenobiotics in a partitioning bioreactor in which the partitioning phase is a polymer," Biotechnol. Bioeng. 84, 399-405, 2003 [More information].

A.J. Daugulis, B.G. Amsden, J. Bochanysz, and A. Kayssi, "Delivery of benzene to Alcaligenes xylosoxidans by solid polymers in a two-phase partitioning bioreactor," Biotech. Letters 25, 1203-1207, 2003 [More information].

Barbara G. Stubbe, Ferenc Horkay, Brian Amsden, Wim E. Hennink, Stefaan C. De Smedt, and Jo Demeester, "Tailoring the swelling pressure of degrading dextran hydroxyethyl methacrylate hydrogels," Biomacromolecules 4, 691-695, 2003 [More information].

A. Hatefi and B. Amsden, "Camptothecin delivery systems," Pharm. Res. 19, 10, 1387-1397, 2002 [More information].

A. Hatefi and B. Amsden, "Biodegradable injectable in-situ forming drug delivery systems," J. Control. Release 80, 9-28, 2002 [More information].

B. Amsden, "Modeling solute probe diffusion in polymer solutions," Polymer 43, 5, 1623-1630, 2002 [More information].

H.M. Younes, and B. Amsden, "Interferon-g therapy: Evaluation of routes of administration and delivery systems," J. Pharm. Sci. 91, 1, 2-17, 2002 [More information].

B. Amsden, K. Grotheer, and D. Angl, "Influence of polymer Ionization degree on solute diffusion in polyelectrolyte gels," Macromolecules 35, 3179-3183, 2002 [More information].

B. Amsden, "Diffusion in polyelectrolyte hydrogels: Application of an obstruction-scaling model to solute diffusion in calcium alginate," Macromolecules 34, 1430-1435, 2001 [More information].

B. Amsden, "Constant release from a swollen polyelectrolyte gel," Proceed. Int'l.Symp. Controlled Release of Bioactive Materials, Paris, France 750-751, 2000.

B. Amsden and N. Turner, "Diffusion characteristics of calcium alginate gels," Biotech. Bioeng 65, 605-610, 1999 [More information].

B. Amsden, "The production of uniformly sized polymer microspheres," Pharm. Res. 16, 1140-1143, 1999 [More information].

B.G. Amsden, "An obstruction-scaling model for diffusion in homogeneous hydrogels," Macromolecules 32, 874-879, 1999 [More information].

B.G. Amsden, "Diffusion within hydrogels. Mechanisms and models," Macromolecules 31, 23, 8382-8395, 1998 [More information].

B.G. Amsden, "Solute diffusion in hydrogels. An examination of the retardation effect," Polymer Gels and Networks 6, 1, 13-43, 1998.

B.G. Amsden and M.F.A. Goosen, "An examination of factors affecting the size, distribution, and release characteristics of polymer microbeads made using electrostatics," J. Control. Release 43, 183-196, 1997.

B.G. Amsden, "Osmotically activated protein release from electrostatically generated polymer microbeads," AIChE Journal 42, 3253-3266, 1996.

A.O. Okhamafe, B. Amsden, W. Chu, and M. Goosen, "Modulation of protein release from chitosan-alginate microcapsules using a pH-sensitive polymer," J. Microencapsulation 13, 497-508, 1996.

B. G. Amsden and M.F.A. Goosen, "Transdermal delivery of peptide and protein drugs: An overview," AIChE Journal 41, 1833-2012, 1995.

B. Amsden and Y. Cheng, "Generic peptide delivery systems based on osmotically rupturable monoliths," J. Control. Release 33, 99-105, 1995.

B.G. Amsden, Y. Cheng, and M. Goosen, "A mechanistic study of the release of osmotically active agents from elastomeric monoliths," J. Controlled Release 30, 21-32, 1994.

B.G. Amsden and Y. Cheng, "Enhanced fraction releasable above percolation threshold from monoliths containing osmotic excipients," J. Control. Release 31, 45-56, 1994.

Polk, B. Amsden, F. DeYao, T. Peng, and M. Goosen, "Chitosan-alginate microcapsules for oral protein drug delivery," J. Pharmaceutical Sciences 84, 178-185, 1994.

D. Poncelet, B. Bugarski, B. Amsden, J. Zhu, R. Neufeld, and M.F.A. Goosen, "A parallel plate electrostatic droplet generator: parameters affecting microbead size," Applied Microbiology and Biotechnology 41, 1994.

Bugarski, B. Amsden, R.J. Neufeld, D. Poncelet, and M.F.A. Goosen, "Effect of electrode geometry and charge on the production of polymer microbeads by electrostatics," Canadian Journal of Chemical Engineering 72, 517-521, 1994.

X. Zhang, U.P. Wyss, D. Pichora, B. Amsden, and M. Goosen, "Controlled release of albumin from biodegradable poly(DL-lactide) cylinders," J. Control. Release 25, 61-69, 1993.

L. Timbart and B.G. Amsden, "Functionalizable biodegradable photocrosslinkable elastomers based on 2-oxepane-1,5-dione," J Polym Sci A Polym Chem 46, 24, 8191-8199.

S. Sharifpoor and B. Amsden, "Release of a water-soluble agent from low viscosity biodegradable, injectable oligomers is driven by osmotic pressure," Eur J Pharm Biopharm 65, 2007, 336–345, [More information].

Patents

B.G. Amsden, "Biodegradable Elastomer and Method of Preparing Same," US patent 6,984,393, 2006.

W.L. Hunter, and B.G. Amsden, "Composition and methods of Paclitaxel for treating psoriasis," US patent 6,515,016, 2003.

B.G. Amsden, R. Liggins, "Methods for Microsphere Production," U.S. Patent 6,224,794 B1, 2001.

B.G. Amsden and Y. Cheng, "Polymer-Based Drug Delivery System," U.S. Patent No. 5,626,877, 1997.

B.G. Amsden and Y. Cheng, "Polymer-Based Drug Delivery System," U.S. Patent No. 5,302,397, 1994.