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Stephen D. Waldman, Ph.D., P.Eng.

Tel: (613) 533-2896, (613) 549-6666 x6384 (Lab)
Fax: (613) 533-6489, (613) 549-2529 (Lab)
Email: waldman@me.queensu.ca
Office: McLaughlin Hall 205

Refereed Publications

55.	Usprech J, Chu G, Giardini-Rosa R, Martin K, Waldman SD(2012). Optimizing the therapeutic potential of ATP for cartilage tissue engineering. Cartilage, In press.
54.	Kaupp JA, Weber JF, Waldman SD (2012). Mechanical stimulation of chondrocyte seeded agarose hydrogels. Journal of Visualized Experiments, In press.
53.	Zhao Y, Waldman SD, Flynn LE(2012). The effect of serial passaging on the proliferation and differentiation of bovine adipose-derived stem cells. Cells, Tissues, Organs, DOI: 10.1159/000329254.
52.	Kunz M, Waldman SD, Rudan JF, Bardana D, Stewart AJ (2012). Computer-assisted mosaic arthroplasty using patient-specific instrument guides: A case report. Knee Surgery, Sports Traumatology, Arthroscopy, DOI: 10.1007/s00167-011-1638-2.
51.	Inoue J, Kunz M, Hurtig MB, Waldman SD, Stewart AJ (2011). Automated planning of computer assisted mosaic arthroplasty. Medical Imaging Computing and Computer Assisted Intervention – MICCAI 2011 14(Part 1):267-274.
50.	Hayami JWS, Waldman SD, Amsden BG(2011). A photocurable hydrogel-elastomer composite scaffold with bi-continuous morphology for cell encapsulation. Macromolecular Bioscience 11(12):1672-1683.
49.	Surrao DC, Khan AA, McGregor AJ, Amsden BG, Waldman SD (2011). Can microcarrier expanded chondrocytes synthesize functional tissue? Tissue Engineering, Part A 17(15/16):1959-1967.
48.	McGregor AJ, Amsden BG, Waldman SD (2011) Chondrocyte repopulation of the zone of death induced by osteochondral harvest. Osteoarthritis and Cartilage 19(2):242-248.
47.	Surrao DC, Hayami JWS, Waldman SD, Amsden BG (2010). Self-crimping, biodegradable, electrospun polymer mircofibres. Biomacromolecules 11(12):3624-3629.
46.	Lievers WB, Poljsak AS, Waldman SD, Pilkey AK (2010). Effects of dehydration-induced structural and material changes on the apparent modulus of cancellous bone. Medical Engineering & Physics 32(8):921-925. .
45.	Lievers WB, Petryshyn A, Poljsak AS, Waldman SD, Pilkey AK (2010). Specimen diameter and “side artifacts” in cancellous bone evaluated using end-constrained elastic tension. Bone 47(2):371-377.
44.	Waldman SD, Usprech J, Flynn LE, Khan AA (2010). Harnessing the purinergic receptor pathway to develop functional engineered cartilage constructs. Osteoarthritis and Cartilage 18(6):864-872.
43.	Fan JCY, Waldman SD (2010). The effect of intermittent static biaxial tensile strains on tissue engineered cartilage. Annals of Biomedical Engineering 38(4):1672-1682.
42.	Hamilton DJ, Pilliar RM, Waldman SD, Kandel RA (2010).Effect of circumferential constraint on nucleus pulposus tissue in vitro. The Spine Journal 10(2):174-183.
41.	Stevenson M, Waldman SD, Lai YL (2010). Design and modeling of a multi-axial mechanical cell stimulator. Journal of Intelligent Material Systems and Structures 21(2):213-220.
40.	Hayami JWS, Surrao DC, Waldman SD, Amsden BG (2010). Design and characterization of a composite scaffold for ligament tissue engineering. Journal of Biomedical Materials Research A 92A(4):1407-1420.
39.	Lievers WB, Waldman SD, Pilkey AK (2010). Minimizing specimen length in elastic testing of end-constrained cortical bone. Journal of the Mechanical Behavior of Biomedical Materials 3(1):22-30.
38.	Kunz M, Devlin S, Gong RH, Inoue J, Waldman SD, Hurtig M, Abolmaesumi P, Stewart J (2009). Predication of the repair surface over cartilage defects: A comparison of three methods in a sheep model. Medical Imaging Computing and Computer Assisted Intervention - MICCAI 2009 12(Part 1):75-82.
37.	Dare EV, Griffith M, Poitras P, Kaupp JA, Waldman SD, Carlsson DJ, Dervin G, Mayoux C, Hincke MT (2009). Genipin cross-linked fibrin hydrogels for human articular cartilage tissue engineered regeneration. Cells, Tissues, Organs 190(6):313-325.
36.	Grynpas MD, Waldman SD, Holmyard D, Bushinsky DA (2009). Genetic hypercaliuric stone-forming rats have a primary decrease in bone mineral density and strength. Journal of Bone and Mineral Research 24(8):1420-1426.
35.	Khan AA, Suits JMT, Kandel RA, Waldman SD (2009). The effect of continuous culture on the growth and structure of tissue engineered cartilage. Biotechnology Progress 25(2):508-515.
34.	Pietak A, Gauthier S, McGregor A, Olescheck R, Waldman SD (2008). Are micropatterned substrates for directed cell organization an effective method to create ordered 3D tissue constructs? Journal of Tissue Engineering and Regenerative Medicine 2(7):450-453.
33.	Suits JMT, Khan AA, Waldman SD (2008). Glycogen accumulation in tissue engineered cartilage. Journal of Tissue Engineering and Regenerative Medicine 2(6):340-346.
32.	Kaupp JA, Waldman SD (2008). The effects of mechanical vibrations on articular chondrocytes in high-density culture. Proceedings of the Institution of Mechanical Engineers. Part H, Journal of Engineering in Medicine 222(5):695-703.
31.	Pietak A, Waldman SD (2008). Seeing cells as a phase of matter: Exploring statistical mechanics to describe cell patterning. Physical Biology 5(1):016007 (10 pages).
30.	Yuen FLY, Zak G, Waldman SD, Docoslis A (2008). Morphology of fibroblast cells grown on substrates formed by dielectrophoretically aligned carbon nanotubes. Cytotechnology 56(1):9-17.
29.	Waldman SD, Usmani Y, Tse MY, Pang SC (2008). Differential effects of natriuretic peptide stimulation on tissue-engineered cartilage. Tissue Engineering PartA 14(3):441-448.
28.	Lievers WB, Lee V, Arsenault SM, Waldman SD, Pilkey AK (2007). Volumetric shrinkage of cancellous bone measured at two levels of dehydration. Journal of Biomechanics 40(9):1903-1909.
27.	Waldman SD, Couto DC, Grynpas MD, Pilliar RM, Kandel RA (2007). Multi-axial mechanical stimulation of tissue engineered cartilage. European Cells & Materials Journal 13:66-75.
26.	Moreno LD, Waldman SD, Grynpas MD (2006). Sex differences in long bone fatigue using a rat model. Journal of Orthopaedic Research 24(10):1926-1932.
25.	Kandel RA, Grynpas MD, Pilliar RM, Lee J, Waldman SD, Zalzal P, Hurtig MB (2006). Repair of osteochondral defects with biphasic cartilage-calcium polyphosphate constructs in a sheep model. Biomaterials 27(22):4120-4131.
24.	Waldman SD, Couto DC, Grynpas MD, Pilliar RM, Kandel RA (2005). A single application of cyclic loading can accelerate matrix deposition and enhance the properties of tissue-engineered cartilage. Osteoarthritis and Cartilage 14(4):323-330 .
23.	Wise LM, Waldman SD, Kasra M, Cheung R, Binnington A, Kandel RA, White LM, Grynpas MD (2005). The effect of zoledronate on bone quality in the treatment of aseptic loosening of hip arthroplasty in the dog. Calcified Tissue International 77(6):367-375.
22.	Waldman SD, Lee JM (2005). Effect of sample geometry on the apparent biaxial mechanical behaviour of planar connective tissues. Biomaterials 26(35):7504-7513.
21.	Djokoto D, Tomlinson G, Waldman SD, Grynpas MD, Cheung AM (2004). Relationship between MRTA, DEXA and QUS. Journal of Clinical Densitometry 7(4):448-456.
20.	Waldman SD, Couto DC, Omelon SJ, Kandel RA (2004). The effect of sodium bicarbonate on extracellular pH, matrix accumulation and morphology of cultured articular chondrocytes. Tissue Engineering 10(11/12):1633-1640.
19.	Waldman SD, Spiteri CG, Grynpas MD, Pilliar RM, Kandel RA (2004). Long-term intermittent compressive stimulation improves the composition and mechanical properties of tissue-engineered cartilage. Tissue Engineering 10(9/10):1323-1331.
18.	Seguin CA, Grynpas MD, Pilliar RM, Waldman SD. Kandel RA (2004). Tissue engineering of nucleus pulposus tissue formed on a porous calcium polyphosphate substrate. Spine 29(12):1299-1307.
17.	Goss PE, Qi S, Josse R, Pritzker KPH, Mendes M, Hu H, Waldman SD, Grynpas MD (2004). The steroidal aromatase inhibitor examestane prevents bone loss in ovariectomized rats. Bone 34(3):384-392.
16.	Waldman SD, Spiteri CG, Grynpas MD, Pilliar RM, Kandel RA (2003). Long-term intermittent shear deformation improves the quality of cartilaginous tissue formed in vitro. Journal of Orthopaedic Research 21(4):590-596.
15.	Waldman SD, Spiteri CG, Grynpas MD, Pilliar RM, Hong J, Kandel RA (2003). Biomechanical effects on cartilaginous tissue formed in vitro. Journal of Bone and Joint Surgery (American) 85A(Supplement 2):101-105.
14.	Waldman SD, Grynpas MD, Pilliar RM, Kandel RA (2003). The use of different chondrocyte populations to modulate the properties of tissue-engineered cartilage. Journal of Orthopaedic Research 21(1):132-138.
13.	Bonyadi M, Waldman SD, Liu D, Aubin JE, Grynpas MD, Stanford WL (2003). Mesenchymal precursor self-renewal deficiency leads to age-dependent osteoporosis in SCA-1/LY-6A null mice. Proceedings of the National Academy of Science 100(10):5840-5845.
12.	Waldman SD, Grynpas MD, Pilliar RM, Kandel RA (2002). Characterization of tissue-engineered cartilage grown on calcium polyphosphate substrates in vitro. Journal of Biomedical Materials Research 62(3):323-330.
11.	Waldman SD, Lee JM (2002). Boundary conditions during biaxial testing of planar connective tissues. Part I: Dynamic behaviour. Journal of Material Science-Materials in Medicine 13(10):933-938.
10.	Waldman SD, Sacks MS, Lee JM (2002). Boundary conditions during biaxial testing of planar connective tissues. Part II: Fibre Orientations. Journal of Materials Science Letters 21(15):1215-1221.
9.	Lee L, Lee JS, Waldman SD, Casper RF, Grynpas MD (2002). Polycyclic aromatic hydrocarbons present in cigarette smoke cause bone loss in an ovariectomized rat model. Bone 30(6):917-923.
8.	Jahangir AR, Lee JM, Waldman SD, Anderson GI (2002). Mechanical characterization of a novel cell stimulating system (CSS) to apply dynamic, uniform and isotropic biaxial strains to cells in vitro. Biomedical Sciences Instrumentation 38:215-220.
7.	Russell KA, Waldman SD, Tompson B, Lee JM (2001). Nasal morphology and shape parameters as predictors of nasal esthetics in individuals with complete unilateral cleft lip and palate. Cleft Palate - Craniofacial Journal 38(5):476-485.
6.	Russell KA, Waldman SD, Lee JM (2000). Video-imaging assessment of nasal morphology in individuals with complete unilateral cleft lip and palate. Cleft Palate - Craniofacial Journal 37(6):542-550.
5.	Waldman SD, Sacks MS, Lee JM (1999). Imposed state of deformation determines local collagen fibre orientation but not apparent mechanical properties. Biomedical Sciences Instrumentation 35:51-56.
4.	Naimark WA, Waldman SD, Anderson RJ, Suzuki B, Pereira CA, Lee JM (1998). Thermomechanical analysis of collagen crosslinking in the developing lamb pericardium. Biorheology 35(1):1-16.
3.	Waldman SD, Bryant JT (1997). Dynamic contact stress and rolling resistance model for total knee arthroplasties. Journal of Biomechanical Engineering 119(3):254-260.
2.	Waldman SD, Cornwall GB, Kiss R, Moore TN, Bowe AJ (1995). Vibration monitoring in wear testing of orthopaedic biomaterials. ASTM STP 1247, p.46-61, Effects of Mechanical Stiffness and Vibration on Wear, Raymond G. Bayer, Ed., American Society for Testing and Materials, Philadelphia, PA.
1.	Waldman SD, Bryant JT (1994). Compressive stress relaxation behaviour of irradiated ultra high molecular weight polyethylene at 37C. Journal of Applied Biomaterials 5(4):333-338.

Book Chapters

3.	Bardana DD, Rudan J, Kunz M, Hurtig MB, Waldman SD, Stewart AJ. Computer assisted mosaic arthroplasty (mosaicplasty). In: A New Coalition for a Challenging Battlefield: Military and Veteran Health Research, Canadian Defence Academy Press, Kingston, Canada, 2012, In press.
2.	Waldman SD, Kandel RA. Bioengineering of osteochondral implants. In: Basic Science, Clinical Repair and Reconstruction of Articular Cartilage Defects: Current Status and Prospects, Brittberg M, Neher S, Marcacci M, Zanasi S, Cancedda R (Eds). Timeo Editore Srl, Bologna, Italy, 2006 , pp.1003-1011.
1.	Kandel RA, Séguin CA, Grynpas MD, Waldman SD, Hurtig MB, Pilliar RM. “Nucleus pulposus tissue can be formed in vitro.” In: Tissue Engineering in Musculoskeletal Clinical Practice, Sandel LJ, Grodzinsky AJ (Eds). American Academy of Orthopaedic Surgeons, Rosemont, IL, 2004, pp.283-293.