CHEE440

Pharmaceutical Technology

Personnel

Instructor

Laura WellsBioSci 4628laura.wells@queensu.ca

TAs

Christopher Rayner16car@queensu.ca

Course Description

Introduction to pharmaceutics and the industrial manufacture of pharmaceutical dosage forms. Topics include the design and preparation of a successful dosage form with respect to the route of administration, and large scale manufacture in a sterile and clean environment. Aspects of chemical kinetics, physical chemistry, physiology, cell biology, mass and heat transfer, and fluid dynamics will be described as they relate to the manufacture of effective dosage forms. (0/12/0/30/0)


Objectives and Outcomes

The objective of this course is to provide the students with an understanding of the application of mathematics, physical chemistry and engineering unit operations in the manufacture and assessment of basic dosage forms.

By the end of this course, students should be able to:

CLO DESCRIPTION INDICATOR
CLO1 Explain the physiological routes of absorption for drugs and the advantages and limitations of each route. KB-BIO(b)
CLO2 Describe and mathematically analyze the absorption, distribution, and elimination of drugs from various dosage forms. KB-BIO(b)
CLO3 Analyze and solve problems involving unit operations in the context of the design and manufacture of tablets, capsules, solutions, suspensions and emulsions. KB-BIO(b)
CLO4 Describe the ethics, safety and regulatory standards around manufacture and regulatory approval of pharmaceutical products. KB-BIO(b)

This course develops the following attribute:
KB-BIO(b): Applies foundations of science and engineering to analyze and solve biological, physiological, pharmaceutical, and/or environmental problems or processes

Relevance to the Program

This elective course, offered at the 4th year level, applies foundations of mathematics, science, and engineering in the pharmaceutical setting and provides bio/physiological insight for biomedical engineering applications.  

Course Structure and Activities

3 lecture hours and 1 tutorial hour per week.  Times and locations can be found on SOLUS. 

Resources

Recommended Textbook: The Design and Manufacture of Medicines, Michael E. Aulton & Kevin M.G. Taylor, 5th Edition.

All course lecture slides, assignments and tutorials will be posted on onQ.